The science behind beautiful lips.

Macdermol® Lips is indicated for patients seeking to enhance lip volume, redefine lip contours, or correct asymmetries, providing natural and balanced results.

This dermal filler is formulated with hyaluronic acid of the highest purity available in the industry, featuring a safe and effective dual cross-linking system that significantly reduces the risk of migration and granuloma formation. It offers excellent tissue integration, blending seamlessly with the lips' natural structure to deliver balanced and refined enhancement.

The technology

Astagen Therapeutics® developed the innovative X-Click technology - A physical cross-linking method that uses no chemical agents, preserving biocompatibility, safety, and the natural properties of HA.

In Macdermol® Lips, X-Click is combined with chemical cross-linking to create a dual cross-linking system.

This approach enhances gel durability, ensures excellent tissue integration, natural look and dramatically reduces the risk of migration and granuloma formation.

  • Protected from structural damages thanks to an optimized sterilization process, the HA in MACDERMOL® LIPS has an optimal average size in terms of beneficial effects on the extracellular matrix. 

  • Clinical data indicate that MACDERMOL® LIPS has a lower rate of adverse events in comparison with other competitors.

Technical Informations

••• COMPOSITION: Non-animal hyaluronic acid. ¹

••• HA CONCENTRATION: 20 mg/ml

••• HA MOLECULAR WEIGHT: Between 3 and 4 millions Dalton

••• CROSS-LINKING: X-Click Technology + BDDE:

••• CROSS-RATE: ●●●○○

••• INDICATION: For increasing lips volume and redefining lip contours

••• NEEDLE DIAMETER: 27 G

••• DURATION OF EFFECT: 6 to 9 months ²     

••• ADMINISTRATION: Linear threading technique into the submucosa of the lips.

••• PACKAGING: 1ml prefilled syringe.

¹ A version with 0,3% of lidocaine is also available on demand.

² Average duration depending on several factors such as patient's skin quality, patient's lifestyle, injection technique of the practitioner, and volume injected.