For a deep, long lasting skin hydration.

Hyaluronic acid (HA), a major component of the skin, is fundamental to retain water and maintain healthy skin tone, elasticity, and a smooth, youthful appearance.

​With age and many other factors (such as daily stress, sun exposure, pollution, smoke, alcohol, lack of sleep, nutritional deficiencies, hormonal change, frost, wind, etc.), the natural levels of HA decrease, especially on the face, neck, décolleté and hands. The skin loses elasticity and firmness, becomes thinner and dry, and fine lines appear on its surface.

​Topical creams can temporarily moisturise the superficial layers of the skin but cannot deliver and maintain deep hydration. MACDERMOL® HYDRO is an injectable gel that will make it possible to provide an immediate, durable and profound skin hydration, creating a long-lasting fresh, natural look.

  • High concentration of non-animal, high molecular weight hyaluronic acid (15 mg/ml).

  • Particularly recommended for patients:

    • Who want to prevent skin ageing

    • Exposed to environmental stress (sun, pollution, smoke, air-conditioning etc.)

    • With dry skin

    • Prone to hormonal imbalance

  • Multi-puncture technique (0.05 ml, 1 cm apart) into the mid-dermis.

    MACDERMOL® HYDRO can be regularly injected without any risk of short- or long-term adverse events which can occur with repetitive injections of dermal fillers. 

    * A topical, needle-free version, classified as sterile cosmetic, is also available on demand. This version is administered through microneedling technique, needleless delivery systems (iontophoresis, ultrasonophoresis, electroporation, etc.) or percutaneously after stratum corneum removal by laser or dermabrasion.

  • MACDERMOL® HYDRO attracts and retains water in the skin and increases the synthesis of new HA and collagen. This dual effect makes it possible to create an immediate and durable deep skin hydration. 

The technology

  • Protected from structural damages thanks to an optimized sterilization process, the HA in MACDERMOL® FINE LINES has an optimal average size in terms of beneficial effects on the extracellular matrix. 

  • Clinical data indicate thatMACDERMOL® FINE LINES has a lower rate of adverse events in comparison with other competitors.

Technical Informations


••• COMPOSITION:   Non-animal Hyaluronic acid    

••• HA CONCENTRATION:   15 mg/ml                       

••• INDICATION:  Restore skin hydration.

••• INJECTION ZONES:  Full face, neck, décolleté, back of hands

••• INJECTION DEPTH: Superficial to mid dermis / Mid to keep dermis

••• ADMINISTRATION:  Multi-puncture or linear threading technique.

••• NEEDLE DIAMETER:   30 G

••• PROTOCOLE:    2 to 3 sessions at interval of 4-6 weeks apart, maintenance session every 6 months.

••• PACKAGING:  1 or 3 ml pre-filled syringe    

••• SECONDARY PACKAGING: Sterilized medical grade blister in carton box    

••• STORAGE:  Between +2°C and +25°C    

••• SHELF LIFE: 3 years